Nitrofurantoin serious side effects. Stop using Nitrofurantoin and call your doctor at once if you have a serious side effect such as:

  • diarrhea that is watery or bloody
  • shortness of breath, running out of breath easily
  • sudden chest pain or discomfort, wheezing, dry cough or hack
  • fever, chills, body aches, unexplained weight loss
  • peripheral neuropathy – numbness, tingling, or pain in your hands or feet
  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)
  • pale skin, easy bruising, confusion or weakness
  • patchy skin color, red spots, or a severe blistering, peeling, and red skin rash
  • severe headache, ringing in your ears, dizziness, vision problems, pain behind your eyes