Apixaban side effects. Call your doctor at once if you have:

  • easy bruising, unusual bleeding (nose, mouth or rectum), bleeding from wounds or needle injections, any bleeding that will not stop
  • heavy menstrual periods
  • headache, dizziness, weakness, feeling like you might pass out
  • red, pink, or brown urine
  • black or bloody stools, coughing up blood or vomit that looks like coffee grounds
  • numbness, tingling, or muscle weakness (especially in your legs and feet)
  • loss of movement in any part of your body