Pregnancy and glucovance. Glucovance is not expected to harm an unborn baby. Similar drugs have caused severe low blood sugar levels in newborns whose mothers used the medicine near the time of delivery. Tell your doctor if you’re pregnant or plan to become pregnant before taking glucovance. The drug may also increase the chance that you will become pregnant. Talk to your doctor about effective birth control methods. It’s not known whether the medicine passes into breast milk or if it could harm a breastfeeding baby.