What is OxyContin? OxyContin is a brand of timed-release OxyCodone, made by Purdue Pharma, that works for up to 12 hours. OxyContin is used to treat moderate to severe pain that is expected to last for an extended period of time. OxyContin is used for around-the-clock treatment of pain. It is not to be used on an “as-needed” basis for pain.